Backhground/story/lore question as per the topic. I know little about the Android setting as the card game is going to be my first foray into it and I've yet to buy any of the novels. I'm just curious if it's possible. I guess that would require said bioroid being sentient, free-willed and completely independent and autonomous from any human agencies, especially any of the corps.

It's totally possible, even (in my opinion) likely.  The writers have always been a little cagey about exactly how autonomous and non-Asimovy bioroids are, with intimations of secret loyalty failsafes, but also obscure exceptions to their programming.  But we do know that Eve is at least sufficiently capable of murder to be a suspect, and even more revealing is the conversation printed on Marilyn's card in Infiltration:

"My concern is that bioroids are not able to harm, or allow through inaction--"

"Directives can be overriden in exigent circumstances, Mr. White." Marilyn sat perfectly still, as only a bioroid could. "I will of course avoid violence if at all possible."

"But you have no compunction against committing a crime?"

"I have very strong compunctions against committing crimes." Marilyn thought about her "children," about Josie and Juan. She thought about getting them back. "But those compunctions will present no difficulty."